A Critical Study on Efficiency of Different Materials for Fluoride Removal from Aqueous Media

Vaishali Tomar and Dinesh Kumar

Fluoride is a persistent and non-biodegradable pollutant that accumulates in soil, plants, wildlife and in human beings. Therefore, knowledge of its removal, using best technique with optimum efficiency is needed. The present survey highlights on efficacy of different materials for the removal of fluoride from water. The most important results of extensive studies on various key factors (pH, agitation time, initial fluoride concentration, temperature, particle size, surface area, presence and nature of counter ions and solvent dose) fluctuate fluoride removal capacity of materials are reviewed.
P3 Feature Image


The chemical nature of water is one of the most imperative criteria that determine its usefulness for a precise need and as such not all the waters are fit for drinking and potable purposes. Apart from fluoride, arsenic and nitrate are few of major water pollutants which cause large scale health issues, but in cutting-edge the most serious pollutant is fluoride [1]. According to the World Health Organization the maximum acceptable concentration of fluoride ions in drinking water lies below 1.5 ppm. Fluoride if taken in small amount is usually beneficial, but the beneficial fluoride concentration range for human health is very small. Depending on the concentrations and the duration of fluoride intake, it could have positive effect on dental caries [2]. On the contrary, long term consumption of water containing excessive amounts of fluoride can lead to fluorosis of the teeth and bones [3]. The excessive intake of fluoride may cause dental [4] and skeletal disorders [5]. Fluoride ion is attracted by positively charged calcium ion in teeth and bones due to its strong electronegativity which results in dental, skeletal and no skeletal forms of fluorosis i.e. high fluoride ingestion, in children as well as adults. Fluorosis in mild version can be evidenced by mottling of teeth and in high version by embrittlement of bones and neurological damage [6], in some of the cases it may even interfere with carbohydrates, proteins, vitamins and mineral metabolism and to DNA creation as well if intake excessively [7]. Studies have shown that major of the Kidney diseases have a great inclination of toxicity of fluoride. On high doses and short term exposure fluoride can exterminate the kidney function. Several research groups have also shows that fluoride can interfere with the function of pineal gland as well as of brain. Pineal gland is one of the major fluoride accrued site in body with concentration more than that of teeth and bones. Workers exposed to high fluoride concentration areas are diagnosed with bladder cancer [8]. Various diseases such as osteoporosis, arthritis, brittle bones, cancer, infertility, brain damage, Alzheimer syndrome, and thyroid disorder can attack human body on excessive intake of fluoride [9]. Fluoride contamination in ground water is a world-wide issue, and some cost effective technologies are required to eliminate excess fluoride in water. The occurrence of high fluoride concentrations in groundwater and risk of fluorosis associated with using such water for human consumption is a problem faced by many countries, notably India, Sri Lanka, and China, the Rift Valley countries in East Africa, Turkey, and parts of South Africa. Conventionally, the fluoride was removed from contaminated water is by liming and accompanying precipitation of fluoride [10]. Various other methods used for the defluoridation of water are ion-exchange [11], precipitation with iron (III) [12], activated alumina [13], alum sludge [14], calcium [15] is widely examined. In addition reverse osmosis [16,17] and electro coagulation [18]. Many of these methods didn’t get used on large scale because various unfavourable factors such as high operational and maintenance cost, generation of toxic by-products (pollution) and due to complex treatment. Authors discussed pros and cons of different techniques for defluoridation and it was concluded that the effective method is coagulation but it does not help in bringing down the fluoride concentration at desired level. On the other hand membrane process is expensive in terms of installation and operation cost, there are also more chances of fouling, scaling or membrane degradation. The electrochemical techniques are not popular due to high cost during installation and maintenance.

One of the most popular techniques for defluoridation that is used in countries like India, Kenya, Senegal and Tanzania is Nalgonda technique. In this technique, calculated quantities of alum, lime and bleaching powder are mixed with water, after mixing the water is processed with flocculation, sedimentation, filtration and disinfection. The entire operation takes about 2–3 hours for around 200 people in batches. Disadvantages of this technique is reported that treated water has high residual aluminium concentration (2–7 mg/L) then the WHO standard of 0.2 mg/L [19-21]. Among these methods, adsorption is the most suitable and widely used technique due to its simple operation, and the availability of a wide range of adsorbents [22].

In this review, an extensive list of adsorbents literature has been compiled. It is evident from a literature survey of about 140 recent papers that low-cost sorbents have demonstrated outstanding removal capabilities for fluoride. In particular, nanomaterial based adsorbents might be a promising adsorbents for environmental and purification purposes.

Go to:


Remediation materials

Alumina and aluminium

Among the adsorbents, activated alumina has been an effective adsorbent for defluoridation of water. Different studies have been focus on this. For the fluoride removal from water Acidic alumina [23], amorphous Al(OH)3, gibbsite or alumina (Al2O3) [24] have been used. It was found that this adsorbent react fluoride at pH range 3–8 with fluoride concentration 1.9 -19 mg/L. At pH 5.5-6.5, maximum fluoride uptake was observed 9 mol/kg. At lower pH, fluoride uptake decreased due to the preferential formation of AlFx soluble species but at higher pH, OH displaced F from the solid Al(OH)3 so the amount of fluoride adsorbed to complexes declined towards zero between pH 6–8. At lower rate, same reaction was followed with gibbsite. At pH 5–7, maximum fluoride removal was found 16.3 mg/g. Due to the electrostatic repulsion in acidic solutions, adsorption of fluoride was retarded. At higher pH, fluoride adsorption on alum occurred due to electrostatic repulsion of fluoride ion to the negatively charged surface of alumina; competition for active sites by excusive amount of hydroxide ion [25]. The Langmuir and Freundlich isotherm models have been described the equilibrium behaviours of the adsorption process. So it was conclude that defluoridation by alumina occurred by nonspecific adsorption. The value of zeta potential for α- Al2O3 was also investigated. At 25°C and pH 5–6, maximum fluoride removal was occurred. From the zeta potential measurement, it was achieved that fluoride adsorbed onto α- Al2O3 by replacing hydroxyl ions from positively charged surfaces and through hydrogen bond [26]. Adsorption capacity of activated alumina (AA) (grad OA −25) was also studied for defluoridation of aqueous solution. At pH 7, adsorption capacity was obtained 1450 mg/kg [27]. Defluoridation increased at pH 4–7 but decreased thereafter. At pH >7, silicates and hydroxyl ions were considered to compete with F ions for alumina exchange sites but at pH < 7, alumina fluoro complexes were formed in the presence of aluminium ions in the treated water. The potential of metallurgical grade alumina (MGA) for defluoridation was investigated at different condition [28]. The effect of temperature on zeta potential and fluoride adsorption was observed at α- Al2O3/aqueous solution interface [29]. Comparison between the adsorption capacities of the untreated hydrated alumina (UHA) and thermally treated hydrated alumina (THA) were obtained from the hydrolysis of locally manufactured aluminium sulphate for defluoridation [30]. The capacity was found 23.7 mg F/g and 7.0 mg F/g for THA and UHA, respectively at pH 4–9. The potential of alumina for fluoride removal from aqueous solution was explained by several other researchers [31-34].

In the recent study, the application of the new HPLC–UVVIS method used in speciation analysis of aluminum form Al(III) ion, aluminum complexes with fluorides and iron in groundwater samples. Based on the obtained results of groundwater samples analysis, the separation of iron in the retention time ≈ 3.7, was obtained. The proposed method is selective for aluminum fluoride complexes and Al(III) in the pH conditions of their occurrence. The paper presents the possible types of transformation of aluminum hydroxyl forms and aluminum sulfate complexes by the reaction of the sample with mobile phase. An indirect method for the determination of aluminum in the form of aluminum sulfate was proposed [35]. See Table 1 for details.

Table 1

Adsorption capacities (ACand other parameters for the removal of fluoride by Alumina and aluminium

AdsorbentAC (mg/g)CR (mg/L)pHRef.

Acidic alumina





Activated alumina (α- Al2O3)





Activated alumina (Grade OA-25)





Metallurgical grade alumina




Al(OH)3 (Al2O3.xH2O) (THA and UHA)24 and 75-307 ± 0.3[30]

Modified activated alumina

To improve the adsorption capacity of alumina, it has been modified. For the modification of it, it has been impregnated by La(III) and Y(III) [36]. Comparison was witnessed between La(III) and Y(III) impregnated alumina and original alumina for the adsorption of fluoride. Lanthanum hydroxide supported on alumina has also been investigated foe defluoridation [37]. The adsorption capacity of alumina impregnated lanthanum hydroxide was 48 mg/g, which was higher than original alumina 23–25 mg/g. Defluoridation by impregnated alumina was explained by ion exchange process between anion and hydroxide group on surface material. Adsorption was found to increase with decreasing of fluoride concentration from 130 mg/L to 0.57 mg/L at pH 5.7-8.0. The sorbed fluoride ions were eluted from the adsorbent with 10 mL of 0.1 M NaOH and column could be reused after being conditioned with 10 mL of 1 × 10−3 M HCl. The surface of alumina was also impregnated with alum for defluoridation [38]. At pH 6.5, the adsorption of fluoride was found 92.6% and then decreased with further increased in pH. To improve the efficiency of alumina for defluoridation of aqueous solution, it modified by coating of copper oxide. The adsorption capacity of copper oxide coated alumina was mentioned in Table 2, which was higher than unmodified activated alumina [39]. Magnesia amended activated alumina [40,41] and calcium oxide modified activated alumina [42] was also used for fluoride removal from water. See Table 2 for details.

Table 2

Adsorption capacities (ACand other parameters for the removal of fluoride by modified activated alumina

AdsorbentAC (mg/g)CR (mg/L)pHRef.

La(III) impregnated on alumina


276 -300



Alum-impregnated activated alumina





Copper oxide coated alumina


10- 15


Magnesia-amended activated alumina





Calcium oxide-modified activated alumina101.01-10005.5[42]

Iron-based adsorbents

Iron-based materials have been investigated for fluoride removal from water. Polypyrrole (PPy)/Fe3O4 magnetic nanocomposites is novel adsorbent in fluoride removal [43]. It was found that presence of chloride and nitrate ions had negligible effect on fluoride adsorption while sulphate and phosphate ions reduced fluoride adsorption because of competitive interaction. It was found that fluoride, sulphate, phosphate ions form inner sphere complexes and they competed for the same active sites of adsorption. Fluoride removal found to be increased with increase in polypyrrole/magnetite (adsorbent) dose. Fluoride uptake increased with increase in solution pH from 2 to 6. Up to 97% of the adsorbed fluoride on the PPy/Fe3O4 nanocomposites was desorbed at pH 12. The adsorption process was endothermic in nature and proceeded by ion-exchange mechanism. To understand the mechanism of fluoride removal, electro coagulation is a method of applying direct current to sacrificial electrodes that [44] are submerged in an aqueous solution and in the acidic condition dissolving aluminum Al(III) is predominant and aluminum hydroxide has tendency soluble. And electro coagulation is pH dependent and pH ranging from 6 to 8, the defluoridation process was found to be efficient. The fluoride removal mechanisms were investigated based on the solution speciation (Al and Al–Fe complexes) and dried sludge characteristics in the electro coagulator. Fluoride removal by amorphous Fe/Al mixed hydroxides was evaluated [45]. At pH 7.5, mixed Fe/Al samples were prepared by the increase of Al content in Fe(OH)3 matrix increase the surface area. The fluoride adsorption followed first order kinetics and intraparticle diffusion model. The sorption process followed both Langmuir and Freundlich isotherm models. The thermodynamic studies showed fluoride sorption to be spontaneous and exothermic in nature. Adsorption and desorption studies were also conducted to gain an insight into the adsorption mechanism on Fe/Al hydroxide surface. The formation of new complexes on the fluoride adsorbed on adsorbent surface was confirmed through spectral analyses. The other anions like phosphate, sulphate and arsenate concentration have adverse effect on fluoride removal efficiency of adsorbent. The adsorbent regenerated with 0.5 M NaOH, maximum regeneration of 80.5% was obtained.

Granulated mixture of Fe-Al-Ce nano adsorbent for fluoride removal by spraying Fe-Al-Ce nano-adsorbent suspension onto glass beads in a fluidized bed was developed [46]. It was found that fluoride adsorption capacity was 2.22 mg/g at pH 7 and initial fluoride concentration of 1 × 10−3 M using the coated granules as adsorbent. The active site for fluoride adsorption was the hydroxyl groups on the Fe-Al-Ce surface. With the increasing coating amount the adsorption capacity increased while the stability of the granule decreased. The natural stilbite zeolite modified with Fe(III) used as adsorbent for the removal of excess fluoride from the drinking water [47]. It was studied from the batch adsorption studies that fluoride concentration can be reduced down to the very low level of 1 mg/L under the optimum conditions. From the study of XPS and EDX, it was concluded that Fe(III) is impregnated on the natural stilbite zeolite and the fluoride is adsorbed on the Fe(III)-stilbite zeolite. And the result of desorption and regeneration showed that the exhausted Fe(III)-stilbite zeolite can be regenerated using 1 M HCl as eluent and the regenerated samples still remain the good adsorptive performance. The fluoride adsorption on Fe(III)-STI is well described by the Langmuir adsorption model, and the maximum adsorption capacity is 2.31 mg/g. The natural STI zeolite is an environment-friendly adsorbent with lower chemical consumption and waste release and operating costs.

For the effectiveness of iron-impregnated granules ceramics in defluoridation of water, it was prepared by simple granulation procedure at room temperature. Both granular ceramics FeSO4.7H2O and granular ceramic (Fe2O3) adsorbents was used for defluoridation of aqueous solution [48]. It was found granular ceramics FeSO4.7H2O is more effective than granular ceramic (Fe2O3) for fluoride removal. The adsorption experiments by batch and mini column scale to test the potential of granular ferric hydroxide for removal of various ions including fluoride was studied [49]. The fluoride adsorption onto granular ferric hydroxide was again found pH dependent. The fluoride capacity decreased with increasing value of pH. The fluoride has the highest adsorption capacity (1.8 mmol/g) and it followed by arsenate (0.9 − 1.0 mmol/g) and phosphate (0.65 − 0.75 mmol/g). The decreases were sharp at above pH 8, as the surface charge of the sample became more negative. The fluoride did not affect arsenate uptake by the adsorbent as fluoride is not a triprotic acid and does not compete for the same sites as arsenate. The synthetic siderite used as a sorbent for fluoride removal [50]. In experiments with an adsorbent dosage of 5 g/L, which was up to 1.775 mg/g and an initial F concentration was 20 mg/L at 25°C. The presence of chloride and nitrate has less effect on fluoride adsorption, while phosphate ion has affected F − removal capacity from aqueous solution. Co-precipitation of ferric hydroxide with fluoride was caused by dissolution of pristine synthetic siderite and subsequent oxidization of Fe(II) ions. A novel bimetallic oxide adsorbent was synthesized by the co-precipitation of Fe(II) and Ti(IV) sulphate solution using ammonia titration at room temperature for fluoride removal from water [51]. Mg-doped nano ferrihydrite powder [52], Fe(III) modified montmorillonite [53], iron rich laterite [54], as an adsorbents for F removal from aqueous solutions. See Table 3 for details.

Table 3

Adsorption capacities (ACand other parameters for the removal of fluoride by Ironbased adsorbents

AdsorbentAC (mg/g)AD (g/L)CR (mg/L)pHRef.

PPy/Fe3O4 nanocomposite

17.6 − 22.3





Fe/Al hydroxide






Fe-Al-Ce nanoadsorbent






Stilbite zeolite modified with Fe(III)






GC(FeSO4.7H2O), GC(Fe2O3)

2.16, 1.70





Synthetic Siderite






Fe―Ti oxide nano-adsorbent






Mg-doped nano ferrihydrite powder






Fe(III) modified montmorillonite12-103.5-9.0[53]

Calcium-based adsorbents

Calcium has a good affinity for fluoride anion and it has been used for fluoride removal [55]. Crushed limestone (99% pure calcite) used as an adsorbent for fluoride removal by batch studies and surface-sensitive techniques from solutions with high fluoride concentration ranging from 3 to ~2100 mg/L. With different techniques, such as atomic force microscopy (AFM) and X-ray photoelectron spectroscopy (XPS) as well as ζ potential measurements, the authors were able to confirm that a combination of surface adsorption and precipitation reactions removed fluoride from aqueous systems. The removal capacity of fluoride was dependent on calcite surface area. Activated and ordinary quick lime as adsorbents used for fluoride removal from water [56]. When initial concentration was 50 mg/L, the removal of fluoride was 80.6% at optimum conditions from synthetic solution. Langmuir maximum sorption capacity of activated quick lime for fluoride was found 16.67 mg/g. The removal of fluoride was found due to chemisorption and precipitation which was confirmed through scanning electron microscopy (SEM) micrographs and X-ray diffraction (XRD). Aluminium hydroxide impregnated limestone as a adsorbent used for fluoride removal from water [57]. At pH 2, the adsorption in case of modified lime stone was decreased. The maximum sorption capacities of the limestone and aluminium hydroxide impregnated limestone were found 43.10 mg/g and 84.03 mg/g, respectively. The adsorption method was used for fluoride removal from aqueous solution by Apatitic tricalcium phosphate [58]. The fluoride uptake by various calcium phosphate minerals [59], calcium aluminate (CA) [60] was reported. See Table 4 for details.

Table 4

Adsorption capacities (ACand other parameters for the removal of fluoride by Calciumbased adsorbents

AdsorbentAC (mg/g)CR (mg/L)pHRef.

Quick Lime




Lime stone & Al(OH)3 impregnated lime stone

43.10 & 84.03




Apatitic tricalcium phosphate





Calcium Aluminate (CA)4.378.93-11[60]

Other metal oxides/hydroxides/oxyhydroxides, mixed metal oxides, metal- impregnated oxides as adsorbents

An inorganic cerium based adsorbent used for fluoride removal [61] and showed sorption capacity for fluoride. Fluoride removal results at low pH were very fruitful. In the fluoride removal, hydroxyl group of cerium based adsorbent played vital role. To facilitate the adsorption of different cations and anions, the metal oxyhydroxide have surface oxygen which differs in the number of coordinating metal ions and the property of oxide minerals was found as advantages for fluoride removal from water [62]. Refractory grade bauxite feed bauxite, manganese ore and hydrated oxides of manganese ores used as adsorbents for fluoride removal from water. Experiments showed that refractory grade bauxite had high fluoride removal efficiency in comparison to other three adsorbents. With pH up to 5.5, the percentage of fluoride adsorption onto refractory grade bauxite was found to increase but decreased with increase in pH. The adsorption process was found to be exothermic hence the adsorption efficiencies decreased with increase of temperature. To obtain CeO2-TiO2/SiO2 surface, sol–gel method was employed and used to determine its potential for fluoride removal [63]. The adsorption capacity for fluoride was found 21.4 mg/g. Magnesia-amended silicon dioxide granules for fluoride removal were investigated [64]. With magnesium chloride solution, the modification of silicon dioxide by wet impregnation was also performed. The adsorption of fluoride depends upon the porous structure and high surface area of the modified granules. At pH range 3 to 4, maximum fluoride adsorption was found and further decreased as pH increased above 10 and the decreased in defluoridation was found due to the change in surface charge of the adsorbent. At pH 3, maximum defluoridation capacity was found 12.6 mg/g. The order of the reduction of fluoride adsorption is bicarbonate > sulphate > phosphate.

The reduction of fluoride adsorption was found due to the competition for active sites between these ions or due to the change in pH. Nano-sized superparamagnetic zirconia material (ZrO2/SiO2/Fe3O4, SPMZ) was applied for the sorption of fluoride from water and simulated industrial wastewater [65]. Fluoride removal from water by a mechanochemically synthesized anion clay (meixnerite) and its calcinations product was studied at initial fluoride:meixnerite molar ratios (FI:meix) of 0.1 to 2.0 the theoretical fluoride uptake limit for meixnerite [66].

Al-Ce hybrid adsorbent by co-precipitation method was prepared and used for fluoride removal [67]. The hybrid adsorbent was of amorphous structure with some aggregated nanoparticles which was revealed by SEM and XRD results. For fluoride, the adsorbent capacity of Al-Ce adsorbent was 91.4 mg/g at 25°C. At pH 6, maximum adsorption capacity was achieved. Due to high zero point potential, the adsorbent was effective in fluoride removal from aqueous solution. FTIR analysis and zeta potential measurement confirmed that the hydroxyl and pronated hydroxyl groups on the adsorbent surface were involved in fluoride adsorption at high and low pH solutions, respectively. Gel like titanium hydroxide derived adsorbent from titanium oxysulfate TiO(SO4) used for fluoride removal [68]. At low fluoride concentration the adsorbent exhibited high adsorption potential for fluoride and had selectivity for fluoride ions with coexisting chloride, nitrate and sulphate ions. At pH 3, maximum fluoride adsorption occurred. In case of low fluoride concentration < 0.8 mg/L, the adsorbent was also able to remove fluoride in real waste water. Aluminium titanate (AT) and bismuth aluminate (BA) as a adsorbent [69] used by authors due to high refractivity, low thermal conductivity, low thermal expansion coefficient of aluminium titanate and bismuth aluminate is antacid, nontoxic, water insoluble material which make them suitable for fluoride removal from water. The amounts of fluoride adsorbed by AT and BA were 0.85 and 1.55 mg/g, respectively at 30°C from 4 mg/L initial concentration.

The removal of fluoride from aqueous solution with magnesia (MgO) and magnesia/chitosan (MgOC) composite were used batch equilibrium experiments [70]. It was observed that defluoridation capacity of MgOC composite (4440 mg/F/kg) was appreciably higher than MgO (2175 mg/F/kg). The influence of different parameters such as contact time, co-existing anions and initial fluoride concentration were studied. It was found that MgO composite reached saturation after 30 min while MgO attained equilibrium after 60 min. In the presence of ClSO24 and NO3 ions the defluoridation capacity of MgOC composite was slightly increased while it decreased in presence of HCO3 ions. Defluoridation capacity of both MgO and MgOC composites were found to increase with increase in initial fluoride concentration. The sorption process followed Freundlich isotherm and pseudo-second order kinetics. The mechanism of fluoride removal was mainly governed by adsorption. Thermodynamics parameters (ΔGº, ΔHº and ΔSº) were calculate and values indicate that fluoride adsorption to be feasible, spontaneous and endothermic reaction.

The removal of fluoride by novel adsorbent calcined magnesia with pullulan (cMgOP) composite, an extracellular water soluble microbial polysaccharide was studied [71]. It was found that the surface area and adsorption micropore of the cMgOP composite were increased from 7.6 m2/g and 14 nm for pure MgO to 33 m2/g and 30 nm, respectively. The presence of ClSO24 and NO3 ions has negligible effect in defluoridation capacity because ClSO24 and NO3 ions interfered in fluorine reagent spectrophotometry and showed a small positive effect as to be negligible while significant decrease in presence of HCO3 due to the competition of bicarbonate ions with fluoride ions in the sorption process. Effect of contact time revealed that the adsorption of three adsorbents- cMgOP, MgO and pullulan increased with increasing contact time. The defluoridation capability of cMgOP (4537 mg/F/kg) was 10 times than that of MgO (457 mg/F/kg). At pH 5, maximum defluoridation capacity of 97.6% was obtained. From the thermodynamic parameters, sorption process was found to be spontaneous and endothermic. Particle diffusion model was the best to describe the adsorption of fluoride on cMgOP.

Hybrid process was applied that combined the adsorption on conventional solid adsorbents such as aluminium and zirconium oxide along with specific donnan dialysis for defluoridation of ground water [72]. It was found that adsorption was not dependent on pH and ionic strength of water to be treated. Donnan dialysis pilot was equipped with specific anion exchange membranes to reduce electrolyte leakage and thus increased in mineralization of treated water. By this treatment cation composition of treated water was not modified but all the anion except chloride was partially eliminated and substituted chloride ions.

The use of magnesium titanate as an adsorbent for fluoride removal was examined [73]. The amount of fluoride adsorbed from 4 mgL-1 of fluoride solution was found to be 0.029 mg/g. The influence of different parameters such as initial concentration of adsorbent, adsorbent dose, agitation time, co-ions and temperature on defluoridation was studied. The percentage of fluoride removal increased with increase in initial concentration of fluoride, temperature, and adsorbent dose and agitation time up to 40 min. Wide range of pH and high temperature ranges were found as the optimum conditions for fluoride adsorption. The experimental data fitted satisfactorily (r > 0.97) to Langmuir isotherm. Thermodynamic parameters such as ΔHº, ΔSº and ΔGº concluded the adsorption was endothermic. Moreover the mechanism of adsorption was found to be physisorption from the magnitude of enthalpy change 20–45 KJ/mol. Defluoridation of water using bauxite adsorbent was studied [74]. The optimum adsorbent dose was found to be 5 g/100 mL, the equilibrium contact time was found to be 75 min and maximum adsorption obtained at pH 6. Maximum fluoride removal was found to be 94.2% at optimum conditions. Langmuir isotherm fitted well for defluoridation of water using bauxite.

In very recent study, bauxite as an adsorbent for the removal of fluoride from contaminated ground water was used. Adsorption experiments with respect to variation in time, pH, adsorbate and concentrations of other anions namely nitrate, sulfate, carbonate, and phosphate were carried out. To get a better insight into the mechanism of adsorption they were characterized bauxite before and after fluoride adsorption by XRD, FTIR and SEM–EDX. An adsorption rate was rapid and followed first order kinetics with intraparticle diffusion as the rate determining step. They were also estimated thermodynamic parameters (ΔH°, ΔS° and ΔG°) which are indicating that the adsorption was spontaneous and exothermic in nature [75]. Mn-Ce oxide adsorbent by co-precipitation method was prepared [76] and studied the role of prepared adsorbent in fluoride removal from the sorption isotherms. It has been shown that the maximum sorption capacities of fluoride on the powdered and granular Mn-Ce adsorbent were 137.5 and 103.1 mg/g.

In our lab, we are also synthesizing Mn-Zr, Mn-Ce-Zr, Mn-Ti-Ce etc. as nano adsorbent with high sorption capacity for fluoride removal from potable water. In this study, the sorption isotherms showed that the maximum adsorption capacities of fluoride on the powdered and granular Mn-Zr adsorbent. The sorption experiment was carried out in 250 mL polypropylene flask containing 200 mL of fluoride solution and 0.02 g adsorbent, and flask were shaken at 150 rpm in a shaker at 25°C for 24 h. The adsorption experiment was carried out at the initial fluoride concentration of 10 mg/L while after treatment water has fluoride concentration in range of 5–7 mg/L. The concentration of fluoride in treated water was varied with contact time, concentration of adsorbent, pH, and concentration of fluoride in non-treated water. The individual particle size, as determined by TEM and XRD and the specific surface area of each sample. There is two size ranges as determined by the TEM images given for the samples. This is due to the fact that the Mn-Zr samples possess a very wide size distribution. In real, there is no discreet break between the large and small particles in these samples. The large and small particles are separated here because important information about the exposed surface planes can be determined by examining the large particles while the small particles are too small to view anything of value.

The paper presents a detailed study of the effect of manganese dioxide on the defluoridation potential of disposed earthenware (DEW) of the particle size less than 300 μm. Manganese dioxide was added to DEW with weight content from 0.01 to 0.025%. The defluoridation was investigated in static experiments, at pH 5–11 and with contact time of 35 min. The fluoride removal increased with the increasing content of manganese dioxide. In static sorption, the defluoridation with DEW dispersed with 0.025% of manganese dioxide increased from 1198 to 1888 mg/kg when the pH increased from 5 to 7 [77]. In the simulating equilibrium data, simple kinetic models namely, pseudo I and II order, particle and pore diffusion, Elovich and isothermal models of Langmuir and Freundlich were used. The fluoride removal was investigated in the presence of coexisting ions. It was found that the reduction in fluoride sorption was greater in the presence of SO24 ion than in the presence of HCO3, Cl and NO3. DEW with dispersed manganese dioxide, showed an ability to lower the fluoride concentration to acceptable levels and improved the defluoridation efficiency of unmodified DEW. The spent sorbent was easily regenerated by NaOH solution. See Table 5 for details.

Table 5

Adsorption capacities (ACand other parameters for the removal of fluoride by metal oxides/hydroxides/oxyhydroxidesmixed metal oxidesmetal– impregnated oxides as adsorbents

AdsorbentAC (mg/g)CR (mg/L)pHRef.

Magnesia-amended silicon dioxide




Superparamagnetic sorbent(ZrO2/SiO2/Fe3O4)





Calcined meixnerite





Al-Ce hybrid adsorbent





Aluminium titanate, Bismuth aluminate

3.01, 7.09




Magnesia, Magnesia/chitosan composite

2.2, 4.4




Magnesium Titanate










Mn-Ce oxide adsorbent powdered & granular

79.5 & 45.5




Manganese dioxide with earthenware9.023-67.15[77]

Bio adsorbents

The defluoridation capability of brushite-calcite with two local biosorbents material (grind neem and pipal leaves) was compared [78]. Fluoride concentration was found to be reduced from 5 mg/L to 1.2 mg/L in 90 min and decreased to 1 mg/L in 18 h by brushite calcite while local biosorbents materials reduced the fluoride concentration to 4 mg/L in 90 min and to 3.22 mg/L after 18 h thus indicating the superiority of brushite-calcite to biosorbents (neem and papal leaves). The Cynodon dactylon was prepared from the activated carbon for fluoride removal [79]. The fluoride concentration of 3 mg/L with 1.25 g of adsorbent at neutral pH was found to be removed to 83.77%. Adsorbent was regenerated by 67.4% using 2% NaOH. Fluoride removal was hindered by bicarbonate ions. The sorption of fluoride was found to be spontaneous and endothermic following pseudo-second order kinetics.

The applicability of neodymium-modified chitosan as adsorbents for the removal of excess fluoride from water was investigated [80]. The modified chitosan showed defluoridation capacity at pH 7. The defluoridation capacity increased with increasing temperature which indicated the strong tendency of monolayer formation process to occur. The chloride, sulphate and nitrate showed no significant effect within the concentration range tested. The Langmuir maximum equilibrium sorption was found to be 11.411 – 22.38 mg/g at different temperatures. The defluoridation capacity of chitosan beads was found negligible and it was chemically modified by introducing the multifunctional groups, such as ammonium and carboxylic groups by mean of protonation and carboxylation in order to utilize both amine and hydroxyl groups for fluoride removal. That modified bioadsorbent showed maximum defluoridation capacity at pH 7. The defluoridation capacity of protonated cum carboxylated chitosan beads was found (1800 mg/F/kg), which was higher than raw chitosan beads (52 mg/F/kg). The protonated cum carboxylated chitosan beads removed fluoride by hydrogen bonding [81]. To remove fluoride ions from aqueous solutions eco-friendly conducting polymer/bio-polymer composites viz. polyaniline/chitosan (PANi/Ch) and polypyrrole/chitosan (PPy/Ch) as adsorbents were investigated. Chitosan is one of the promising natural polymers with characteristics such as biodegradability, chemical inertness, good film forming properties and low cost. The system variables studied include initial concentration of the sorbate, agitation time, adsorbent dose, pH, co-ions and temperature. At low pH and high temperature, fluoride removal occurred. The amount of fluoride ion removal increased with a decrease in adsorbent dose due to the availability of higher number of fluoride ions per unit mass of polymer composites, i.e., higher fluoride/composite ratio. According to Langmuir and Freundlich isotherms, the experimental data fitted well. The amounts of fluoride ions adsorbed per unit mass of the adsorbents were found to be 5.9 mg/g for PANi/Ch and 6.7 for PPy/Ch, at 50°C from 10 mg/L fluoride solution. The removal of fluoride ions is an endothermic process was indicated through thermodynamic parameters. The PPy/Ch composite exhibited relatively higher defluoridation capacity than the PANi/Ch composite due to the fact that polypyrrole itself exhibited higher fluoride ions removal capacity than that of polyaniline [82]. Therefore, the corresponding polymer/Ch composites also exhibited the same trend. It is well established that these polymers, in the chloride ion doped form, remove fluoride ions from water via dopant-exchange mechanism. The conducting polymer/Ch composites remove fluoride ions from water through the ion-exchange mechanism using the N-atoms present in both the constituent polymers and this ion- exchange leading to an enhanced fluoride removal. The defluoridation occurred through dopant-exchange mechanism on the N-atoms present in these constituent polymers.

To enhance the fluoride removal capacity from water, Lanthanum incorporated chitosan beads were prepared using precipitation method. At pH 5, maximum adsorption capacity was observed 4.7 mg/g [83]. Waste fungal biomass [84] (Pleuratus astreatus 1804) derived from the laccare fermentation process was used for fluoride removal from water. Batch absorption studies were performed for this experiment and the results revealed that bioadsorbent demonstrated the ability to absorb fluoride from water. The sorption obeyed the pseudo-first-order rate equation and the fluoride sorption was found to be dependent on the aqueous phase pH. At lower pH, the fluoride uptake was observed to be greater. A detailed fluoride adsorption study in packed columns with chitin or a chitin-based biocomposite is reported [85]. A novel cost effective defluoridation method that is based on surface modification of rice husk ash (RHA) by coating aluminum hydroxide [86]. See Table 6 for details.

Table 6

Adsorption capacities (ACand other parameters for the removal of fluoride by Bio adsorbents

AdsorbentAC (mg/g)CR (mg/L)pHRef.

Neodymium-modified chitosan





PANi/Ch, PPy/Ch

5.9, 6.7




Lanthanum incorporated chitosan beads










Rice husk ash (RHA) by coating Al(OH)39-1010-605[86]

Carbon based sorbents

Some researchers used carbon as an adsorbent for fluoride removal. The potential sorption capacity of multi-walled carbon nanotubes (MWCNTs) was investigated as a means of removing fluoride from the drinking water of a number of regions in Iran and from experimental solutions [87]. A novel poly(aniline-co-o-aminophenol) (PAOA) modified carbon felt electrode reactor was designed and investigated for fluoride removal from aqueous solutions [88]. Fishbone charcoal is a moving media adsorption system used for fluoride adsorption [89]. The ratio of attained of attained equilibrium sorbate concentration to the initial sorbate concentration and the fluoride removal capacity of the sorbent were found to vary inversely with the sorbent mass input rate and varied directly with the sorbate flow rate and initial sorbate concentration. The ratio of attained equilibrium sorbate concentration to the initial sorbate concentration found to be a function of the sorbent – sorbent mass input rate ratio. Zirconium impregnated activated charcoals as an adsorbent used for defluoridation [90]. In comparison of plain activated charcoal, the fluoride adsorption capacity of impregnated activated charcoals was 3–5 times higher. Maximum fluoride uptake showed by zirconium impregnated coconut fibre charcoal and followed by groundnut shell and coconut shell charcoals due to its large surface area. Micro/nano-hierarchal web consisting of activated carbon fibres [91] and carbon nano fibres impregnated with Al used as an adsorbent for fluoride removal from wastewater. At pH 5–8, Al-carbon nano fibres was used for treating the wastewater. Granular activated carbon was coated with manganese oxides and used for fluoride removal from water and showed maximum adsorption capacity [92]. The adsorption capacity was three times higher than uncoated granular activated carbon. At pH 3, the fluoride adsorption was observed maximum. Different grades of graphite were used as adsorbents for fluoride removal from water [93]. At appreciable extent, competing anions did not affect fluoride removal. Carbons loaded with specific chemical moieties were prepared from pecan nut shells employing a natural modifier agent obtained from egg shell (CMPNS), which is rich in calcium, for the selective adsorption of fluoride from water [94]. A batch adsorption system was applied to investigate the adsorption of fluoride from aqueous solution by graphene [95]. To the removal of excess fluoride in drinking water using cerium dispersed in carbon (CeDC), a hybrid sorbent which was prepared by carbonization of ammonium cerium sulphate impregnated starch [96].

The importance of Acacia Arabica fruit carbon as an alternative to activated carbon as defluoridation method was investigated [97]. It was concluded that, for the selected domain, the chosen variables agitation time (T), granulometry (G) and adsorbent’s concentration (A) had very significant influence on the process, with increasing importance as followed: G < T < A. The role of three activated carbon adsorbents, BKC, BOC and RSC which were prepared from biomaterials of bergera koenigh (curry leaf seeds), batavia orange and raphanus sativus (garden radish) respectively was investigated [98]. It has been found that upto 4 mg/L fluoride contents can be reduced to permissible level. Maximum contact time was found to be 30 min and optimum dose of adsorbent was 1 g/L. Moreover, at pH 6 maximum defluoridation was observed. Adsorbent was found to be regenerated by passing 0.1 M NaOH solutions. See Table 7 for details.

Table 7

Adsorption capacities (ACand other parameters for the removal of fluoride by Carbon based sorbents

AdsorbentAC (mg/g)CR (mg/L)pHRef.





(PAOA) modified carbon





Al-impregnated hierarchal web of carbon fibres




MnO2-coated granular activated carbon




Various grades of graphite















cerium dispersed in carbon (CeDC)522.8-8.38.0[96]

Natural materials

Some researchers have been used naturally occurring adsorbent for fluoride removal from water due to its low cost availability. The three different coal based sorbents, lignite, fine coke and bituminous coal was used for fluoride removal [99]. At acidic pH, fine coke and bituminous coal showed higher fluoride removal from water. The pH range 6–12 was found favourable for fluoride removal from water in case of lignite. The capacities of coal based adsorbents ranged between 6.9 and 7.44 mg/g. Assam coals were used for fluoride removal by researchers [100]. For 85% fluoride removal, the optimum dose of adsorbent was found to be 1.25 g/100 mL. The fluoride adsorption affected through particle size. Fired clay chips used for fluoride removal [101]. At pH 3 and 9, the maximum amount of fluoride removal after equilibration was 90% and 80%, respectively. South African clays used for fluoride removal from water [102]. For fluoride adsorption, various clay such as bauxite, laterite, palygorskite, bentonite and kaolinite were tested. Clays consisting of substantial amounts of gibbsite or aluminium oxides exhibited best overall potential as fluoride adsorbents. The defluoridation with three types of tamarind seed, pristine (PriTS), purified (PurTS) and polyaniline (Pani) was reported [103]. It has been found that 50% pani coated both in pristine and purified TS materials enhanced the fluoride adsorption efficiency. The defluoridation of water using tamarind seed by domestic water filter was studied [104]. The influence of pH, agitation time, initial fluoride concentration, temperature, particle size and solvent dose were studied for defluoridation. Maximum defluoridation capacity was achieved at pH 7. Tamarindus indica fruit shells (TIFSs) were activated by ammonium carbonate and then carbonized leading to carbon abbreviated as ACA–TIFSC [105]. The defluoridation capacity decreased with increase in initial fluoride concentration, temperature and particle size. Defluoridation followed first order kinetics and Langmuir adsorption isotherm. The hydro-methanolic extract of tamarind fruit pulp in removing of body fluoride burden has been undertaken for study [106]. For this experiment thirty rats were divided into five groups. Low dose, middle dose, high dose of sodium fluoride was received by these groups through orally at the rate of 200 mg/kg body weight daily for four weeks. Rats of low dose, middle dose and high dose group simultaneously received tamarind fruit pulp extract at three doses 25 (low), 50 (medium) and 100 mg (high) per kg body weight orally, respectively. The concentration of fluoride in blood, urine and long bone of experimental rats was monitored to assess the efficacy of the extract. The mean serum fluoride concentration in fluoride exposed rats was 0.145 ± 0.009 and0.783 ± 0.042 g/mL on days 0 and 98. In comparison, fluoride concentrations in tamarind treated rats were 0.179 ± 0.021 and 0.633 ± 0.015; 0.179 ± 0.021 and 0.502 ± 0.025 and 0.176 ± 0.021 and 0.498 ± 0.030 g/mL in low, medium and high dose groups, respectively on day 0 and day 98 of the experiment. There was a significant increase in urinary fluoride excretion from day 28 onwards. The mean fluoride concentration in long bones of treated rats was significantly lower than the values recorded from fluoride exposed rats. Adsorption was carried out by pumice stone [107] as an adsorbent for fluoride removal. See Table 8 for details.

Table 8

Adsorption capacities (ACand other parameters for the removal of fluoride by Natural materials

AdsorbentAC (mg/g)CR (mg/L)pHRef.

Lignite, Fine coke and Bituminous coal





Fired clay chips





Tamarindus indica Fruit Shells (TIFSs)





Pumice stone41103-10[107]


The potential of nano alumina for fluoride removal and was found to be 140 mg/g [108]. Defluoridation studies were conducted under various experimental conditions such as pH, contact time, initial fluoride concentration, temperature and the presence of counter ions. It was noticed that maximum fluoride removal occurred at pH 6.15 and increased with increase in time and initial fluoride concentration. Fluoride adsorption was not significantly affected by temperature variation but was influenced by PO34SO24 and CO23 ions. The sorption isotherm was fitted with Langmuir model and followed pseudo-second order kinetics. Carbon nanotubes (CNTs) as support to deposit Al2O3 and explored the possibility of Al2O3/CNTs for fluoride removal from drinking water [109]. The fluoride removal was occurred on Al2O3/CNTs at pH 5.9-9.0. The adsorption capacity for Al2O3/CNTs was 13.5 times higher than AC-300 carbon and four times higher than that of γ-Al2O3 at equilibrium fluoride concentration of 12 mg/L. The mass of fluoride adsorption for Al2O3/CNTs at pH 6 reached 28.7 mg/g at equilibrium concentration of 50 mg/L. See Table 9 for details.

Table 9

Adsorption capacities (ACand other parameters for the removal of fluoride by Nanosorbents

AdsorbentAC (mg/g)CR (mg/L)pHRef.

Nano – alumina






Building materials

The potential of building materials towards fluoride removal was observed. The low weight concrete (building material) [110] as an adsorbent for the removal of fluoride from water was used and check their efficacy by vary various parameters. The maximum adsorption of fluoride took place at pH 6.9 but in the acidic medium, less adsorption took place due to the formation of weakly ionised hydrofluoric acid. Another adsorbent i.e. hydrated cement [111] and hardened alumina cement granules [112] for fluoride removal from aqueous solution was observed. See Table 10 for details.

Table 10

Adsorption capacities (ACand other parameters for the removal of fluoride by Building materials

AdsorbentAC (mg/g)AD (mg/g)CR (mg/L)pHRef.

LWC (building material)





Hydrated cement





Hardened alumina cement granules34.410.22.5-100[112]

Apatite and hydroxyapatite

Apatite in different forms has been used for fluoride removal as it showed good prospective for defluoridation. Synthetic nano-hydroxyapatite (n-Hap), biogenic apatite, treated biogenic apatite, geogenic apatite were engaged to evaluate their effectiveness for fluoride removal [113]. The removal of fluoride using synthetic hydroxyapatites (HAps) was investigated. It was found that small sized (HAps) were more efficient than the largest particle size. It was also concluded that the defluoridation efficiency increased with increase in the dose of HAps and contact time but decreased with increase in initial fluoride concentration and pH. The nanostructure of hydroxyapatite from combined ultrasonic and microwave technique and examined its role in defluoridation [114,115]. The effects of low molecular weight organic acids (LMWOAs) on the defluoridation capacity of nanosized hydrpxyapatite (nHAP) from aqueous solution were investigated [116]. Cellulose@hydroxyapatite (HA) nanocomposites were prepared in NaOH/thiourea/urea/H2O solution via situ hybridization [117]. Aluminum-modified hydroxyapatite (Al-HAP) was also used for defluoridation [118]. Phosphogypsum (PG) was utilized to prepare hydroxyapatite nanoparticles with high purity. nHAP derived from PG exhibits excellent adsorption capacity for fluoride [119]. See Table 11 for details.

Table 11

Adsorption capacities (ACand other parameters for the removal of fluoride by Apatite and hydroxyapatite

AdsorbentAC (mg/g)AD (g/L)CR (mg/L)pHRef.

Synthetic nano hydroxyapatite






Biogenic apatite


Treated biogenic apatite


Geogenic apatite








Nano sized hydroxyapatite






Cellulose@hydroxyapatite nanocomposites






Al-modified hydroxyapatite (Al-HAP)






nHAp derived from PG19.74-40.81110-502-11[119]

Industrial waste adsorbent

Extensive industrial actions generates enormous amount of solid waste materials as by–products. One of the advantageous uses of these wastes is to convert them as economical sorbents for detoxification of water. For the fluoride removal from aqueous solution, the industrial waste like spent bleaching earth (SBE) is used as a adsorbent [120]. The waste SBE was obtained from the oil industry, and acid and alkaline were used to recover it. In addition, the optimum conditions obtained in this study were tested on Kuhbonan (one of the regions of Iran whose fluoride level has been reported between 2.28 and 5.4 mg/L) water. At pH 7, the maximum fluoride adsorption was obtained and an equivalent time of 180 min. When the fluoride initial concentration in water increased, fluoride removal efficiency decreased. The maximum adsorption capacity of RSBE was 0.6 mg/g fluoride (2.5–8 mg/F/L, 10 g RSBE/L and pH 7). Adsorption of fluoride on waste carbon slurry (a fertilizer industry waste) was investigated [121]. Activated titanium rich bauxite was also another adsorbent which was used for defluoridation of water [122]. See Table 12 for details.

Table 12

Adsorption capacities (ACand other parameters for the removal of fluoride by Industrial waste adsorbent

AdsorbentAC (mg/g)AD (g/L)CR (mg/L)pHRef.

Regenerated spent bleaching earth






Waste carbon slurry






Activated titanium rich bauxite3.7-4.12-506.0[122]

Zirconium based adsorbents

The defluoridation performance and adsorption mechanism of a high capacity hydrous zirconium oxide [123], meso-structured zirconium phosphate (MZrP) [124] adsorbents were investigated. The need of treatment of large volume water samples could be met by the super paramagnetic properties of the nanoparticles through application of an external magnetic field. Zr(IV) metalloporphyrins possess high selective affinity toward fluoride. The synthesis of a new sorbent consisting of 3-aminopropyl triethoxysilane (APTES) coated magnetic nanoparticles functionalized with a zirconium(IV) porphyrin complex Zr(TCPP)Cl2 [TCPP: tetrakis(4-carboxyphenyl) porphyrin] [125] were used for defluoridation. A novel zirconium(IV)-ethylenediamine (ZrEDA) hybrid material was prepared by mixing aqueous solution of zirconium oxychloride (0.1 M) and aqueous solution of ethylenediamine (0.1 M) following an environmental friendly sol–gel method [126]. zirconium-modified-Na-attapulgite (Zr-A) adsorbent was used for defluoridation [127]. See Table 13 for details.

Table 13

Adsorption capacities (ACand other parameters for the removal of fluoride by Zirconium based adsorbents

AdsorbentAC (mg/g)CR (mg/L)pHRef.

Hydrous zirconium oxide adsorbent

124 -68




Meso-structured zirconium phosphate (MZrP)




Zr(IV)metalloporphyrin grafted Fe3O4 NPs










Miscellaneous adsorbents for defluoridation of water

Bleaching powder as adsorbent for fluoride removal from water was used. It could be used as disinfectant and defluoridation agent. It was found that defluoridation from water occurred due to adsorption by bleaching powder and slightly due to precipitation in the form of calcium fluoride. At pH 6–10, defluoridation from water was occurred by adsorbent dose of 50 g/L [128]. Ti-Ce (9.6 mg/g) and Ti-La (15.1 mg/g) hybrid adsorbents had higher sorption capacities for fluoride than TiO2 (1.7 mg/g) adsorbent [129]. The sorption capacity decreased with increasing pH from 3 to 9.5. The conducting polypyrrole as adsorbent for the fluoride removal from aqueous solution was studied [130]. The amount of fluoride ion removed per unit mass of the adsorbent at 30°C from 10 mg/L fluoride ion solution was estimated to be 6.37 mg/g. For defluoridation from aqueous solution, Magnesia-loaded fly ash cenospheres was prepared by wet impregnation of fly ash cenospheres with magnesium chloride solution. At pH 3, defluoridation from aqueous solution was observed with adsorbent dose 2.5 mg/L [131]. Aerobic granules (AG) were carboxylated and Ce(III) was incorporated to obtain modified granules (Ce(III)–MAG) for removal of fluoride from aqueous solutions [132]. Besides the above mentioned adsorbents, various other authors also examined the potential of different types of sorbents such as KMnO4 modified activated carbon derived from steam pyrolysis of rice straw [133], hybrid thorium phosphate composite [134], granular acid-treated bentonite [135], Nickel and magnesium hydrotalcite-like compounds (NiAlHT, MgAlHT) [136], etc. for fluoride removal. See Table 14 for details.

Table 14

Adsorption capacities (ACand other parameters for the removal of fluoride by miscellaneous adsorbents

AdsorbentAC (mg/g)CR (mg/L)pHRef.

Bleaching powder





Magnesia loaded fly ash cenospheres





Modified granules (Ce(III)–MAG)





KMnO4 modified carbon15.9202.0[133]
Go to:


Studies for the removal of fluoride, using several adsorbents have been summarized briefly in this review. The efficacy of each adsorbent has been examined and discussed. The following conclusions have been made on the basis of literature review:

•Although activated alumina adsorption technology shows higher uptake of fluoride, but it is expensive and its performance is affected by the presence of co-ions in water.

•Rare earth oxide-based materials have shown high fluoride removal efficiency in batch mode but these materials have been found very expensive.

•Carbon based adsorbents have its application in small scale and lack in terms of column operation and/or pilot scale.

•Various natural adsorbents have potential for defluoridation of water but their difficulties in regeneration and low efficiency have also been reported.

•Biosorption is an environmentally friendly technique for fluoride removal utilizing various biomaterials of low cost. However, there are some disadvantages also, which limited its use for removal of low fluoride concentration.

•Nano- adsorbents have been attracted considerable attention in the recent years in fluoride removal and these materials have shown higher fluoride uptake capacity.

•The influence of pH, agitation time, initial fluoride concentration, temperature, particle size, surface area, presence and nature of counter ions and solvent dose were studied for defluoridation with various adsorbents.

•The sorption kinetics was pseudo-second order or pseudo-first order and the equilibrium data fitted well to the adsorption isotherms like Langmuir and Freundlich.

So, the future research should be concentrated in evaluating the efficacy of adsorbents in terms of cost and feasibility for removal of fluoride. It would be worthwhile to study the suitability of different chemicals to regenerates the spent adsorbents.

Go to:


AA: Activated Alumina; MGA: Metallurgical grade alumina; UHA: Untreated hydrated alumina; THA: Thermally treated hydrated alumina; PPy: Polypyrrole; Fe(III)-STI: Fe(III)-stilbite zeolite; AFM: Atomic force microscopy; XPS: X-ray photoelectron spectroscopy; SEM: Scanning electron microscopy; FTIR: Foutier infrared spectroscopy; XRD: X-ray diffraction; CA: Calcium aluminate; SO4: Titanium oxysulfate TiO(SO4); AT: Aluminium titanate; BA: Bismuth aluminate; MgOC composite: Magnesia (MgO) and magnesia/chitosan; enthalpy ΔH0 and entropy ΔS0: Gibbs free energy ΔG0; cMgOP: Calcined magnesia with pullulan; DEW: Disposed earthenware; PPy/Ch: Polyaniline/chitosan (PANi/Ch) and polypyrrole/chitosan; RHA: Rice husk ash; MWCNTs: Multi-walled carbon nanotubes; PAOA: Poly(aniline-co-o-aminophenol); CMPNS: Carbons loaded with specific chemical moieties pecan nut shells; CeDC: Cerium dispersed in carbon; T: Agitation time; G: Granulometry; A: Adsorbent’s concentration; BKC: Bergera koenigh (curry leaf seeds); BOC: Batavia orange; RSC: Raphanus sativus (garden radish); (PriTS: Tamarind seed, pristine; PurTS: Purified; Pani: Polyaniline; TIFSs: Tamarindus indica Fruit Shells; ACA–TIFSC: Ammonium carbonate Tamarindus indica Fruit Shells carbon; CNTs: Carbon nanotubes; LWC: Low weight concrete; n-Hap: Synthetic nano-hydroxyapatite; LMWOAs: Low molecular weight organic acids; Al-HAP: Aluminum-modified hydroxyapatite; PG: Phosphogypsum; SBE: Spent bleaching earth; RSBE: Regenerated spent bleaching earth; MZrP: Meso-structured zirconium phosphate; APTES: 3-aminopropyl triethoxysilane; TCPP: Tetrakis(4-carboxyphenyl) porphyrin; ZrEDA: Zirconium(IV)-ethylenediamine; Zr-A: Zirconium-modified-Na-attapulgite; AG: Aerobic granules; NiAlHT: MgAlHT, Nickel and magnesium hydrotalcite-like compounds; Ce(III)–MAG: Ce(III) modified granules; AC: Adsorption capacity; CR: Concentration range; AD: Adsorbent dose

Go to:

Competing interests

Both the authors declared that there is no competing interest.

Go to:

Authors’ contributions

VT and DK both authors made equally efforts in this paper and have created many of the chemistry related stuffs in this review. Both authors read and approved the final manuscript.

Go to:


The authors are thankful to University Grant Commission (UGC), New Delhi for its financial assistance.

Go to:


  • Amini M, Mueller K, Abbaspour KC, Rosenberg T, Afyuni M, Møller KN, Sarr M, Johnson CA. Statistical modeling of global geogenic fluoride contamination in groundwaters. Environ Sci Technol. 2008;42:3662–3668. doi: 10.1021/es071958y. [PubMed] [CrossRef] [Google Scholar]
  • Mahramanlioglu M, Kizilcikli I, Bicer IO. Adsorption of fluoride from aqueous solution by acid treated spent bleaching earth. J Fluorine Chem. 2002;115:41–47. doi: 10.1016/S0022-1139(02)00003-9. [CrossRef] [Google Scholar]
  • Jamodei AV, Sapkal VS, Jamode VS. Defluoridation of water using inexpensive adsorbents. J Ind Inst Sci. 2004;84:163–171. [Google Scholar]
  • Gonzales C, Hotokezaka H, Karadeniz EI, Miyazaki T, Kobayashi E, Darendeliler MA, Yoshida N. Effects of fluoride intake on orthodontic tooth movement and orthodontically induced root respiration. Am. J Ortho Dentofacial Orthop. 2004;139:196–205. [PubMed] [Google Scholar]
  • Solangi IB, Memon S, Bhanger MI. Removal of fluoride from aqueous environment by modified amberlite resin. J Hazard Mater. 2009;171:815–819. doi: 10.1016/j.jhazmat.2009.06.072. [PubMed] [CrossRef] [Google Scholar]
  • Fan X, Parker DJ, Smith MD. Adsorption kinetics of fluoride on low cost materials. Water Res. 2003;37:4929–4937. doi: 10.1016/j.watres.2003.08.014. [PubMed] [CrossRef] [Google Scholar]
  • Zhou Y, Yu C, Shan Y. Adsorption of fluoride from aqueous solution on La3+ impregnated crosslinked gelatin. Sep Purif Technol. 2004;36:89–94. doi: 10.1016/S1383-5866(03)00167-9. [CrossRef] [Google Scholar]
  • Islam M, Patel RK. Thermal activation of basic oxygen furnace slag and evaluation of its fluoride removal efficiency. Chem Eng J. 2011;169:68–77. doi: 10.1016/j.cej.2011.02.054. [CrossRef] [Google Scholar]
  • Health Effects. http://www.fluoridealert.org/health/
  • Harrison PTC. Fluoride in water: a UK perspective. J Fluorine Chem. 2005;126:1448–1456. doi: 10.1016/j.jfluchem.2005.09.009. [CrossRef] [Google Scholar]
  • Apambire WB, Boyle DR, Michel FA. Geochemistry, genesis, and health implications of fluoriferous groundwaters in the upper regions of Ghana. Environ Geochem. 1997;33:13–24. [Google Scholar]
  • Tressaud A. Fluorine and the Environment: Agrochemicals, Archaeology. Amsterdam; Boston: Elsevier; 2006. (Green Chemistry & Water). (series editor): Advances in Fluorine Science, vol. 2. [Google Scholar]
  • Ghorai S, Pant KK. Equilibrium, kinetics and breakthrough studies for adsorption of fluoride on activated alumina. Sep Purif Technol. 2005;42:265–271. doi: 10.1016/j.seppur.2004.09.001. [CrossRef] [Google Scholar]
  • Sujana MG, Thakur RS, Rao SB. Removal of fluoride from aqueous solution by using alum sludge. J Colloid Interface Sci. 1998;206:94–101. doi: 10.1006/jcis.1998.5611. [PubMed] [CrossRef] [Google Scholar]
  • Huang CJ, Liu JC. Precipitate flotation of fluoride-containing wastewater from a semiconductor manufacturer. Water Res. 1999;33:3403–3412. doi: 10.1016/S0043-1354(99)00065-2. [CrossRef] [Google Scholar]
  • Simons R. Trace element removal from ash dam waters by nanofiltration and diffusion dialysis. Desalination. 1993;89:325–341. doi: 10.1016/0011-9164(93)80145-D. [CrossRef] [Google Scholar]
  • Sehn P. Fluoride removal with extra low energy reverse osmosis membranes: three years of large scale field experience in Finland. Desalination. 2008;223:73–84. doi: 10.1016/j.desal.2007.02.077. [CrossRef] [Google Scholar]
  • Hu CY, Lo SL, Kuan WH. Effect of co-exiting anions on fluoride removal in electrocoagulation process using aluminium electrodes. Water Res. 2003;37:4513–4523. doi: 10.1016/S0043-1354(03)00378-6. [PubMed] [CrossRef] [Google Scholar]
  • Ayoob S, Gupta AK, Bhat VT. A conceptual overview on sustainable technologies for defluoridation of drinking water and removal mechanisms. Crit Rev Environ Sci Technol. 2008;38:401–470. doi: 10.1080/10643380701413310. [CrossRef] [Google Scholar]
  • WHO. Guidelines for drinking-water quality. 3. Geneva: World Health Organisation; 2004. pp. 375–378. 301–303. [Google Scholar]
  • Meenakshi MRC. Fluoride in drinking water and its removal. J Hazard Mater. 2006;137:456–463. doi: 10.1016/j.jhazmat.2006.02.024. [PubMed] [CrossRef] [Google Scholar]
  • Mohapatra M, Anand S, Mishra BK, Giles DE, Singh P. Review of fluoride removal from drinking water. J Environ Manage. 2009;91:67–77. doi: 10.1016/j.jenvman.2009.08.015. [PubMed] [CrossRef] [Google Scholar]
  • Goswami A, Purkait MK. The defluoridation of water by acidic alumina. Chem Eng Res and Des. 2012;90:2316–2324. doi: 10.1016/j.cherd.2012.05.002. [CrossRef] [Google Scholar]
  • Farrah H, Slavek J, Pickering WF. Fluoride interactions with hydrous aluminum oxides and alumina. Aust J Soil Res. 1987;25:55–69. doi: 10.1071/SR9870055. [CrossRef] [Google Scholar]
  • Ku Y, Chiou HM. The adsorption of fluoride ion from aqueous solution by activated alumina. Water Air Soil Pollut. 2002;133:349–361. doi: 10.1023/A:1012929900113. [CrossRef] [Google Scholar]
  • Bahena JLR, Cabrera AR, Valdivieso AL, Urbina RH. Fluoride adsorption onto α-Al2O3 and its effect on the zeta potential at the alumina – aqueous electrolyte interface. Sep Sci Technol. 2002;37:1973–1987. doi: 10.1081/SS-120003055. [CrossRef] [Google Scholar]
  • Ghorai S, Pant KK. Investigations on the column performance of fluoride adsorption by activated alumina in a fixed-bed. Chem Eng J. 2004;98:165–173. doi: 10.1016/j.cej.2003.07.003. [CrossRef] [Google Scholar]
  • Pietrelli L. Fluoride wastewater treatment by adsorption onto metallurgical grade alumina. Anal Chim. 2005;95:303–312. doi: 10.1002/adic.200590035. [PubMed] [CrossRef] [Google Scholar]
  • Valdivieso AL, Bahena JLR, Song S, Urbina H. Temperature effect on the zeta potential and fluoride adsorption at the α-Al2O3/aqueous solution interface. J Colloid Interface Sci. 2006;298:1–5. doi: 10.1016/j.jcis.2005.11.060. [PubMed] [CrossRef] [Google Scholar]
  • Shimelis B, Zewge F, Chandravanshi BS. Removal of excess fluoride from water by aluminum hydroxide. Bull Chem Soc Ethiopia. 2006;20:17–34. [Google Scholar]
  • Bishop PL, Sansoucy G. Fluoride removal from drinking water by fluidized activated alumina adsorption. J Am Water Works Assoc. 1978;70:554–559. [Google Scholar]
  • Choi WW, Cen KY. Removal of fluoride from waters by adsorption. J Am Water Works Assoc. 1979;71:562–570. [Google Scholar]
  • Hao OJ, Huang CP. Adsorption characteristics of fluoride onto hydrous alumina. J Environ Eng. 1986;112:1054–1069. doi: 10.1061/(ASCE)0733-9372(1986)112:6(1054). [CrossRef] [Google Scholar]
  • Fletcher HR, Smith DW, Pivonka P. Modeling the sorption of fluoride onto alumina. J Environ Eng. 2006;132:229–246. doi: 10.1061/(ASCE)0733-9372(2006)132:2(229). [CrossRef] [Google Scholar]
  • Frankowski M. Simultaneous determination of aluminum, aluminum fluoride complexes and iron in groundwater samples by new HPLC–UVVIS method. Microchem J. 2012;101:80–86. [Google Scholar]
  • Wasay SA, Tokunaga S, Park SW. Removal of hazardous anions from aqueous solutions by La(III)- and Y(lll)-impregnated alumina. Sep Sci Technol. 1996;31:1501–1514. doi: 10.1080/01496399608001409. [CrossRef] [Google Scholar]
  • Puri BK, Balani S. Trace determination of fluoride using lanthanum hydroxide supported on alumina. J Environ Sci Health. 2000;35:109–121. doi: 10.1080/10934520009376957. [CrossRef] [Google Scholar]
  • Tripathy SS, Bersillon JJ, Gopal K. Removal of fluoride from drinking water by adsorption onto alum-impregnated activated alumina. Sep Purif Technol. 2006;50:310–317. doi: 10.1016/j.seppur.2005.11.036. [CrossRef] [Google Scholar]
  • Bansiwal A, Pillewan P, Biniwale RB, Rayalu SS. Copper oxide incorporated mesoporous alumina for defluoridation of drinking water. Micropor Mesopor Mat. 2010;129:54–61. doi: 10.1016/j.micromeso.2009.08.032. [CrossRef] [Google Scholar]
  • Shihabudheen MM, Sharma AK, Philip L. Manganese-oxide-coated alumina: A promising sorbent for defluoridation of water. Water Res. 2006;40:3497–3506. doi: 10.1016/j.watres.2006.08.007. [PubMed] [CrossRef] [Google Scholar]
  • Teng SX, Wang SG. Removal of fluoride by hydrous manganese oxide-coated alumina: Performance and mechanism. J Hazard Mater. 2009;168:1004–1011. doi: 10.1016/j.jhazmat.2009.02.133. [PubMed] [CrossRef] [Google Scholar]
  • Camacho LM, Torres A, Saha D, Deng S. Adsorption equilibrium and kinetics of fluoride on sol–gel- derived activated alumina adsorbents. J Colloid Interface Sci. 2010;349:307–313. doi: 10.1016/j.jcis.2010.05.066. [PubMed] [CrossRef] [Google Scholar]
  • Bhaumika M, Leswifia TY, Maity A, Srinivasu VV, Onyango MS. Removal of fluoride from aqueous solution by polypyrrole/Fe3O4 magnetic nanocomposite. J Hazard Mater. 2011;186:150–159. doi: 10.1016/j.jhazmat.2010.10.098. [PubMed] [CrossRef] [Google Scholar]
  • Emamjomeh MM, Sivakumar M, Varyani AS. Analysis and the understanding of fluoride removal mechanisms by an electrocoagulation/flotation (ECF) process. Desalination. 2011;275:102–106. doi: 10.1016/j.desal.2011.02.032. [CrossRef] [Google Scholar]
  • Sujana MG, Soma G, Vasumathi N, Anans S. Studies on fluoride adsorption capacities of amorphous Fe/Al mixed hydroxides from aqueous solutions. J Fluorine Chem. 2009;130:749–754. doi: 10.1016/j.jfluchem.2009.06.005. [CrossRef] [Google Scholar]
  • Chen L, Wu HX, Wang TJ, Jin Y, Zhang Y, Dou XM. Granulation of Fe–Al–Ce nano-adsorbent for fluoride removal from drinking water by spray coating on sand in a fluidized bed. Powder Technol. 2009;193:59–64. doi: 10.1016/j.powtec.2009.02.007. [CrossRef] [Google Scholar]
  • Sun Y, Fang Q, Dong J, Cheng X, Xu J. Removal of Fluoride form drinking water by natural Stilbite Zeolite modified with Fe (III) Desalination. 2011;277:121–127. doi: 10.1016/j.desal.2011.04.013. [CrossRef] [Google Scholar]
  • Chen N, Zhang Z, Feng C, Li M, Zhu D, Sugiura N. Studies on fluoride adsorption of iron-impregnated granular ceramics from aqueous solution. Mater Chem Phys. 2011;125:293–298. doi: 10.1016/j.matchemphys.2010.09.037. [CrossRef] [Google Scholar]
  • Streat M, Hellgardt K, Newton NLR. Hydrous ferric oxide as an adsorbent in water treatment: Part 3: Batch and mini-column adsorption of arsenic, phosphorus, fluorine and cadmium ions. Process Saf. Environ. 2008;86:21–30. doi: 10.1016/j.psep.2007.10.009. [CrossRef] [Google Scholar]
  • Liu Q, Guo H, Shan Y. Adsorption of fluoride on synthetic siderite from aqueous solution. J Fluorine Chem. 2010;131:635–641. doi: 10.1016/j.jfluchem.2010.02.006. [CrossRef] [Google Scholar]
  • Chen L, He BY, He S, Wang TJ, Su CL, Jin Y. Fe-Ti oxide nano-adsorbent synthesized by co-precipitation for fluoride removal from drinking water and its adsorption mechanism. Powder Technol. 2012;227:3–8. [Google Scholar]
  • Mohapatra M, Hariprasad D, Mohapatra L, Anand S, Mishra BK. Mg-doped nano ferrihydrite – A new adsorbent for fluoride removal from aqueous solutions. Appl Surf Sci. 2012;258:4228–4236. doi: 10.1016/j.apsusc.2011.12.047. [CrossRef] [Google Scholar]
  • Bia G, Pauli CPD, Borgnino L. The role of Fe(III) modified montmorillonite on fluoride mobility: Adsorption experiments and competition with phosphate. J Environ Manage. 2012;100:1–9. [PubMed] [Google Scholar]
  • Vithanagea M, Jayarathnaa L, Rajapakshaa AU, Dissanayakea CB, Bootharajub MS, Pradeep T. Modeling sorption of fluoride on to iron rich laterite Colloids and Surfaces A. Physicochem Eng Aspects. 2012;398:69–75. [Google Scholar]
  • Turner BD, Binning P, Stipp SLS. Fluoride removal by calcite: evidence for fluorite precipitation and surface adsorption. Environ Sci Technol. 2005;39:9561–9568. doi: 10.1021/es0505090. [PubMed] [CrossRef] [Google Scholar]
  • Islam M, Patel RK. Evaluation of removal efficiency of fluoride from aqueous solution using quick lime. J Hazard Mater. 2007;143:303–310. doi: 10.1016/j.jhazmat.2006.09.030. [PubMed] [CrossRef] [Google Scholar]
  • Jain S, Jayaram RV. Removal of fluoride from contaminated drinking water using unmodified and aluminium hydroxide impregnated blue lime stone waste. Sep Sci Technol. 2009;44:1436–1451. doi: 10.1080/01496390902766074. [CrossRef] [Google Scholar]
  • Mourabet M, Rhilassi AE, Boujaady HE, Ziatni MB, Hamri RE, Taitai A. Removal of fluoride from aqueous solution by adsorption on Apatitic tricalcium phosphate using Box–Behnken design and desirability function. Appl Surf Sci. 2012;258:4402–4410. doi: 10.1016/j.apsusc.2011.12.125. [CrossRef] [Google Scholar]
  • Yang T, Kim C, Jho J, Kim IW. Regulating fluoride uptake by calcium phosphate minerals with polymeric additives. Colloids and Surfaces A. Physicochem. Eng. Aspects. 2012;401:126–136. [Google Scholar]
  • Sakhare N, Lunge S, Rayalu R, Bakardjiva S, Subrt J, Devotta S, Labhsetwar N. Defluoridation of water using calcium aluminate material. Chem Eng J. 2012;203:406–414. [Google Scholar]
  • Zhongzhi J, Zhonglin C, Min Y, Yu Z, Guibai L. Adsorption of fluoride ion by inorganic cerium based adsorbent. High Technol Lett. 2004;10:83–86. [Google Scholar]
  • Mohapatra D, Mishra D, Mishra SP, Chaudhury GR, Das RP. Use of oxide minerals to abate fluoride from water. J Colloid Interface Sci. 2004;275:355–359. doi: 10.1016/j.jcis.2004.02.051. [PubMed] [CrossRef] [Google Scholar]
  • Xiuru Y, Kuanxiu S, Jianping W, Liuchang H, Zhaohui Z. Preparation of CeO2-TiO2/SiO2 and its removal properties for fluoride ions. J Rare Earth. 1998;16:279–280. [Google Scholar]
  • Zhu P, Wang H, Sun B, Deng P, Hou S, Yu Y. Adsorption of fluoride from aqueous solution by magnesia–amended silicon dioxide granules. J Chem Technol Biotech. 2009;84:1449–1455. doi: 10.1002/jctb.2197. [CrossRef] [Google Scholar]
  • Chang CF, Chang CY, Chang TLHF, Chang CY, Hsu TL. Removal of fluoride from aqueous solution with the superparamagnetic zirconia material. Desalination. 2011;279:375–382. doi: 10.1016/j.desal.2011.06.039. [CrossRef] [Google Scholar]
  • Guo Q, Reardon EJ. Fluoride removal from water by meixnerite and its calcination product. Appl Clay Sci. 2012;56:7–15. [Google Scholar]
  • Liu H, Deng S, Li Z, Yu G, Huang J. Preparation of Al-Ce hybrid adsorbent and its application for defluoridation of drinking water. J Hazard Mater. 2010;179:424–430. doi: 10.1016/j.jhazmat.2010.03.021. [PubMed] [CrossRef] [Google Scholar]
  • Wajima T, Umeta Y, Narita S, Sugawara K. Adsorption behaviour of fluoride ions using a titanium hydroxide- derived adsorbent. Desalination. 2009;249:323–330. doi: 10.1016/j.desal.2009.06.038. [CrossRef] [Google Scholar]
  • Karthikeyan M, Elango KP. Removal of fluoride from water using aluminium containing compounds. J Environ Sci. 2009;21:1513–1518. doi: 10.1016/S1001-0742(08)62448-1. [PubMed] [CrossRef] [Google Scholar]
  • Sundaram CS, Viswanathan N, Meenakshi S. Defluoridation of water using magnesia/chitosan composite. J Hazard Mater. 2009;163:618–624. doi: 10.1016/j.jhazmat.2008.07.009. [PubMed] [CrossRef] [Google Scholar]
  • Kang J, Li B, Song J, Li D, Yang J, Zhan W, Liu D. Defluoridation of water using calcined magnesia/pullulan composite. Chem Eng J. 2011;166:765–771. doi: 10.1016/j.cej.2010.11.031. [CrossRef] [Google Scholar]
  • Garmes H, Persin F, Sandeaux J, Pourcelly G, Mountadar M. Defluoridation of groundwater by a hybrid process combining adsorption and Donnan dialysis. Desalination. 2002;145:287–291. doi: 10.1016/S0011-9164(02)00424-1. [CrossRef] [Google Scholar]
  • Gopal V, Elango KP. Studies on defluoridation of water using magnesium titanate. Ind J Chem Tech. 2010;17:28–33. [Google Scholar]
  • Sujana MG, Anand S. Fluoride removal studies from contaminated ground water by using bauxite. Desalination. 2011;267:222–227. doi: 10.1016/j.desal.2010.09.030. [CrossRef] [Google Scholar]
  • Jamasbian F, Attar SJ, Saini DR. Defluoridation Of Water Using Bauxite Adsorbent. Int J of Engg Res & Indu Appls. 2009;2:247–257. [Google Scholar]
  • Denq S, Liu H, Zhou W, Huang J, Yu G. Mn–Ce oxide as a high-capacity adsorbent for fluoride removal from water. J Hazard Mater. 2011;186:1360–1366. doi: 10.1016/j.jhazmat.2010.12.024. [PubMed] [CrossRef] [Google Scholar]
  • Sivasankar V, Ramachandramoorthy T, Darchen A. Manganese dioxide improves the efficiency of earthenware in fluoride removal from drinking water. Desalination. 2011;272:179–186. doi: 10.1016/j.desal.2011.01.021. [CrossRef] [Google Scholar]
  • Lakshminarayan N, Davangere AG. Evaluation of the water defluoridating potential of Brushite-Calcite and two indigenous bioadsorbent materials. Fluoride. 2011;44:27–29. [Google Scholar]
  • Alagumuthu G, Veeraputhiran V, Venkataraman R. Fluoride sorption using cynodon dactylon-based activated carbon. Hem. Ind. 2011;65(1):23–35. doi: 10.2298/HEMIND100712052A. [CrossRef] [Google Scholar]
  • Yao R, Meng F, Zhang L, Ma D, Wang M. Defluoridation of water using neodymium-modified chitosan. J Hazard Mater. 2009;165:454–460. doi: 10.1016/j.jhazmat.2008.10.052. [PubMed] [CrossRef] [Google Scholar]
  • Viswanathan N, Sundaram C, Meenakshi S. Development of multifunctional chitosan beads for fluoride removal. J Hazard Mater. 2009;167:325–331. doi: 10.1016/j.jhazmat.2008.12.123. [PubMed] [CrossRef] [Google Scholar]
  • Karthikeyan M, Kumar KKS, Elango KP. Batch sorption studies on the removal of fluoride ions from water using eco-friendly conducting polymer/bio-polymer composites. Desalination. 2011;267:49–56. doi: 10.1016/j.desal.2010.09.005. [CrossRef] [Google Scholar]
  • Jagtap S, Yenkie MK, Das S, Rayalu S. Synthesis and characterization of lanthanum impregnated chitosan flakes fopr fluoride removal in water. Desalination. 2011;273:267–275. doi: 10.1016/j.desal.2010.12.032. [CrossRef] [Google Scholar]
  • Ramanaiah SV, Mohan SV, Sarma PN. Adsorptive removal of fluoride from aqueous phase using waste fungus (Pleurotus ostreatus 1804) biosobent: Kinetics evalutionEcol Eng. 2007;31:47–56. doi: 10.1016/j.ecoleng.2007.05.006. [CrossRef] [Google Scholar]
  • Rodriguez JLD, Vladimir A, Barrios E, Mendez JRR. Removal of fluoride from drinking water by a chitin-based biocomposite in fixed-bed columns. J Fluorine Chem. 2012;140:99–103. [Google Scholar]
  • Ganvir V, Das K. Removal of fluoride from drinking water using aluminum hydroxide coated rice husk ash. J Hazard Mater. 2011;185:1287–1294. doi: 10.1016/j.jhazmat.2010.10.044. [PubMed] [CrossRef] [Google Scholar]
  • Ansari M, Kazemipour M, Dehghani M, Kazemipour M. The defluoridation of drinking water using multi-walled carbon nanotubes. J Fluorine Chem. 2011;132:516–520. doi: 10.1016/j.jfluchem.2011.05.008. [CrossRef] [Google Scholar]
  • Cui H, Qian Y, An H, Sun C, Zhai J, Li Q. Electrochemical removal of fluoride from water by PAOA modified carbon felt electrodes in a continuous flow reactor. Water Res. 2012;46:3943–3950. doi: 10.1016/j.watres.2012.04.039. [PubMed] [CrossRef] [Google Scholar]
  • Bhargava DS, Killedar DJ. Fluoride adsorption on fishbone charcoal through a moving media adsorber. Water Res. 1992;26:781–788. doi: 10.1016/0043-1354(92)90009-S. [CrossRef] [Google Scholar]
  • Janardhana C, Rao GN, Sathish RS, Kumar PS, Kumar VA, Madhav MV. Study on defluoridation of drinking water using zirconium ion impregnated activated charcoals. Indian J Chem Technol. 2007;14:350–354. [Google Scholar]
  • Gupta AK, Deva D, Sharma A, Verma N. Adsorptive removal of fluoride by micro-nanohierarchal web of activated carbon fibers. Ind. Eng. Chem. Res. 2009;48:9697–9707. doi: 10.1021/ie801688k. [CrossRef] [Google Scholar]
  • Ma Y, Wang SG, Fan M, Gong WX, Gao BY. Characteristics and defluoridation performance of granular activated carbons coated with manganese oxides. J Hazard Mater. 2009;168:1140–1146. doi: 10.1016/j.jhazmat.2009.02.145. [PubMed] [CrossRef] [Google Scholar]
  • Karthikeyan M, Elango KP. Removal of fluoride from aqueous solution using graphite: A kinetic and thermodynamic study. Indian J Chem Technol. 2008;15:525–532. [Google Scholar]
  • Montoya VH, Montoya LAR, Petriciolet AB, Morán MAM. Optimizing the removal of fluoride from water using new carbons obtained by modification of nut shell with a calcium solution from egg shell. Biochem Eng J. 2012;62:1–7. [Google Scholar]
  • Li Y, Zhang P, Du Q, Peng X, Liu T, Wang Z, Xi Y, Zhang W, Wang K, Zhu H, Wu D. Adsorption of fluoride from aqueous solution by Grapheme. J Colloid Interface Sci. 2011;363:348–354. doi: 10.1016/j.jcis.2011.07.032. [PubMed] [CrossRef] [Google Scholar]
  • Sivasankar V, Murugesh S, Rajkumar S, Darchen A. Cerium dispersed in carbon (CeDC) and its adsorption behavior: A first example of tailored adsorbent for fluoride removal from drinking water. Chem Eng J. 2013;214:45–54. [Google Scholar]
  • Kishore M, Hanumantharao Y. Validation of defluoridation method with “Acacia Arabica plant by product through 2n factorial experimentation- A statistical approach. Int J Appl Biol & Pharma Technol. 2010;1:1230–1235. [Google Scholar]
  • Rao VS, Chakrapani C, Babu CS, Rao KS, Rao MN, Sinha D. Studies on sorption of fluoride by prepared activated Kaza’s carbons. Der Pharma Chemica. 2011;3:73–83. [Google Scholar]
  • Sivasamy A, Singh KP, Mohan D, Maruthamuthu M. Studies on defluoridation of water by coal-based sorbents. J Chem Technol Biotechnol. 2001;76:717–722. doi: 10.1002/jctb.440. [CrossRef] [Google Scholar]
  • Borah L, Dey NC. Removal of fluoride from low TDS water using low grade coal. Indian J Chem Technol. 2009;16:361–363. [Google Scholar]
  • Moges G, Zewge F, Socher M. Preliminary investigations on the defluoridation of water using fired clay chips. J African Earth Sci. 1996;22:479–482. doi: 10.1016/0899-5362(96)00030-9. [CrossRef] [Google Scholar]
  • Coetzee PP, Coetzee LL, Puka R, Mubenga S. Characterisation of selected South African clays for defluoridation of natural waters. ISSN 0378–4738. Water S.A. 2003;29:331–338. [Google Scholar]
  • Subramanian E, Ramalakshmi RD. Pristine, purified and polyaniline-coated tamarind seed (Tamarindus indica) biomaterial powders for defluoridation: synergism and enhancement in fluoride adsorption by polyaniline coating. J Sci Ind Res. 2010;69:621–628. [Google Scholar]
  • Sivasankar V, Rajkumar S, Murugesh S, Darchen A. Influence of shaking or stirring dynamic methods in the defluoridation behaviour of activated tamarind fruit shell carbon. Chem Eng J. 2012;197:162–172. [Google Scholar]
  • Murugan M, Subramanian E. Studies on defluoridation of water by Tamarind seed, an unconventional biosorbent. J Water Health. 2006;4:453–461. [PubMed] [Google Scholar]
  • Dey S, Swarup D, Saxena A, Dan A. In vivo efficacy of tamarind (Tamarinds indica) fruit extract on experimental fluoride exposure in rats. Res Vet Sci. 2011;91(3):422–425. doi: 10.1016/j.rvsc.2010.09.013. [PubMed] [CrossRef] [Google Scholar]
  • Asgaria G, Roshanib B, Ghanizadeh G. The investigation of kinetic and isotherm of fluoride adsorption onto functionalize pumice stone. J Hazard Mater. 2012;217-218:123–132. [PubMed] [Google Scholar]
  • Kumar E, Bhatnagara A, Kumar U, Sillanpää M. Defluoridation from aqueous solutions by nano-alumina: Characterization and sorption studies. J Hazard Mater. 2011;186:1042–1049. doi: 10.1016/j.jhazmat.2010.11.102. [PubMed] [CrossRef] [Google Scholar]
  • Li YH, Wang S, Cao A, Zhao D, Zhang X, Xu C, Luan Z, Ruan D, Liang J, Wu D, Wei B. Adsorption of fluoride from water by amorphous alumina supported on carbon nanotubes. Chem Phys Lett. 2001;350:412–416. doi: 10.1016/S0009-2614(01)01351-3. [CrossRef] [Google Scholar]
  • Oguz E. Equilibrium isotherms and kinetics studies for the sorption of fluoride on light weight concrete materials. Colloids Surf. . A: Physicochem Eng Aspects. 2007;295:258–263. doi: 10.1016/j.colsurfa.2006.09.009. [CrossRef] [Google Scholar]
  • Kagne S, Jagtap S, Dhawade P, Kamble SP, Devotta S, Rayalu SS. Hydrated cement: A promising adsorbent for the removal of fluoride from aqueous solution. J Hazard Mater. 2008;154:88–95. doi: 10.1016/j.jhazmat.2007.09.111. [PubMed] [CrossRef] [Google Scholar]
  • Ayoob S, Gupta AK. Insights into isotherm making in the sorptive removal of fluoride from drinking water. J Hazard Mater. 2008;152:976–985. doi: 10.1016/j.jhazmat.2007.07.072. [PubMed] [CrossRef] [Google Scholar]
  • Gao S, Cui J, Wei Z. Study on the fluoride adsorption of various apatite materials in aqueous solution. J Fluorine Chem. 2009;130:1035–1041. doi: 10.1016/j.jfluchem.2009.09.004. [CrossRef] [Google Scholar]
  • Gao S, Sun R, Wei Z, Zhao H, Li H, Hu F. Size-dependent defluoridation properties of synthetic hydroxyapatite. J. Fluorine. Chem. 2009;130:550–556. doi: 10.1016/j.jfluchem.2009.03.007. [CrossRef] [Google Scholar]
  • Poinern GEJ, Ghosh MK, Ng YJ, Issa TB, Anand S, Singh P. Defluoridation behavior of nanostructured hydroxyapatite synthesized through an ultrasonic and microwave combined technique. J Hazard Mater. 2011;185:29–37. doi: 10.1016/j.jhazmat.2010.08.087. [PubMed] [CrossRef] [Google Scholar]
  • Wang Y, Chen N, Wei W, Cui J, Wei Z. Enhanced adsorption of fluoride from aqueous solution onto nanosized hydroxyapatite by low-molecular-weight organic acids. Desalination. 2011;276:161–168. doi: 10.1016/j.desal.2011.03.033. [CrossRef] [Google Scholar]
  • Yu X, Tong SM, Zuo J. Removal of fluoride from drinking water by cellulose@hydroxyapatite nanocomposites. Carbohyd. Polym. 2013;92:269–275. doi: 10.1016/j.carbpol.2012.09.045. [PubMed] [CrossRef] [Google Scholar]
  • Nie Y, Hu C, Kong C. Enhanced fluoride adsorption using Al (III) modified calcium hydroxyapatite. J Hazard Mater. 2012;233-234:194–199. [PubMed] [Google Scholar]
  • Zhang D, Luo H, Zheng L, Wang K, Li H, Wang Y, Feng H. Utilization of waste phosphogypsum to prepare hydroxyapatite nanoparticles and its application towards removal of fluoride from aqueous solution. J Hazard Mater. 2012;241-242:418–426. [PubMed] [Google Scholar]
  • Malakootian M, Fatehizadeh A, Yousefi N, Ahmadian M, Moosazadeh M. Fluoride removal using regenerated spent bleaching earth (RSBE) from gound water: Case study on Kuhbonan water. Desalination. 2011;277:224–249. [Google Scholar]
  • Gupta VK, Ali I, Saini VK. Defluoridation of wastewaters using waste carbon slurry. Water Res. 2007;41:3307–3316. doi: 10.1016/j.watres.2007.04.029. [PubMed] [CrossRef] [Google Scholar]
  • Das N, Pattanaik P, Das R. Defluoridation of drinking water using activated titanium rich bauxite. J Colloid Interface Sci. 2005;292:1–10. doi: 10.1016/j.jcis.2005.06.045. [PubMed] [CrossRef] [Google Scholar]
  • Mohan XDD, Pittman CU Jr, Yang S. Remediating fluoride from water using hydrous zirconium oxide. Chem Eng J. 2012;198-199:236–245. [Google Scholar]
  • Swaina SK, Patnaikb T, Singha VK, Jhaa U, Patelc RK, Dey RK. Kinetics, equilibrium and thermodynamic aspects of removal of fluoride from drinking water using meso-structured zirconium phosphate. Chem Eng J. 2011;171:1218–1226. doi: 10.1016/j.cej.2011.05.030. [CrossRef] [Google Scholar]
  • Poursaberi T, Hassanisadi M, Torkestani K, Zare M. Development of zirconium (IV)-metalloporphyrin grafted Fe3O4 nanoparticles for efficient fluoride removal. Chem Eng J. 2012;189-190:117–125. [Google Scholar]
  • Swaina SK, Mishrab S, Patnaikc T, Pateld RK, Jhaa U, Deye RK. Fluoride removal performance of a new hybrid sorbent of Zr(IV)–ethylenediamine. Chem Eng J. 2012;184:72–81. [Google Scholar]
  • Zhanga G, Hea Z, Xu W. A low-cost and high efficient zirconium-modified-Na-attapulgite adsorbent for fluoride removal from aqueous solutions. Chem Eng J. 2012;183:315–324. [Google Scholar]
  • Kagne S, Jagtap S, Thakare D, Devotta S, Rayalu SS. Bleaching powder: a versatile adsorbent for the removal of fluoride from aqueous solution. Desalination. 2009;243:22–31. doi: 10.1016/j.desal.2008.04.012. [CrossRef] [Google Scholar]
  • Li Z, Deng S, Zhang X, Zhou W, Huang J, Yu G. Removal of fluoride from water using titanium-based adsorbents. Front Environ Sci Engg China. 2010;4:414–420. doi: 10.1007/s11783-010-0241-y. [CrossRef] [Google Scholar]
  • Karthikeyan M, Elango KP. Removal of fluoride ions from aqueous solution by conducting polypyrrol. J Hazard Mater. 2009;167:300–305. doi: 10.1016/j.jhazmat.2008.12.141. [PubMed] [CrossRef] [Google Scholar]
  • Xu X, Li Q, Cui H, Pang J, Sun L, An H, Zhai J. Adsorption of fluoride from aqueous solution on magnesia-loaded fly ash cenospheres. Desalination. 2011;272:233–239. doi: 10.1016/j.desal.2011.01.028. [CrossRef] [Google Scholar]
  • Wang XH, Song RH, Yang HC, Shi YJ, Dang GB, Yang S, Zhao Y, Sun XF, Wang SG. Fluoride adsorption on carboxylated aerobic granules containing Ce(III) Bioresource Tech. 2013;127:106–111. [PubMed] [Google Scholar]
  • Daifullah AAM, Yakout SM, Elreefy SA. Adsorption of fluoride in aqueous solutions using KMnO4-modified activated carbon derived from steam pyrolysis of rice straw. J Hazard Mater. 2007;147:633–643. doi: 10.1016/j.jhazmat.2007.01.062. [PubMed] [CrossRef] [Google Scholar]
  • Islam M, Mishra PC, Patel R. Fluoride adsorption from aqueous solution by a hybrid thorium phosphate composite. Chem Eng J. 2011;166:978–985. doi: 10.1016/j.cej.2010.11.087. [CrossRef] [Google Scholar]
  • Ma Y, Shi F, Zheng X, Ma J, Gao C. Removal of fluoride from aqueous solution using granular acid-treated bentonite (GHB): Batch and column studies. J Hazard Mater. 2011;185:1073–1080. doi: 10.1016/j.jhazmat.2010.10.016. [PubMed] [CrossRef] [Google Scholar]
  • Núnez MLJ, Riosa MS, Gardunob JC, Gutiérrez MTO. Effect of grain size and interfering anion species on the removal of fluoride by hydrotalcite-like compounds. Chem Eng J. 2012;181-182:371–375. [Google Scholar]